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Cell biology
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In the Nucleus, Genes’ Activity Might Depend on Their Location
Using a new CRISPR-based technique, researchers are examining how the position of DNA within the nucleus affects gene expression and cell function.
In the Ticking of the Embryonic Clock, She Finds Answers
Renee Reijo Pera has spent decades uncovering how the timing of embryonic development contributes to health and disease.
The Physics of Glass Opens a Window Into Biology
The physicist Lisa Manning studies the dynamics of glassy materials to understand embryonic development and disease.
Cells Talk in a Language That Looks Like Viruses
Disease-causing viruses and message-carrying vesicles sit at the ends of a spectrum of membranous particles that cells release.
Oxygen and Stem Cells May Have Reshaped Early Complex Animals
An unlikely team offers a controversial hypothesis about what enabled animal life to get more complex during the Cambrian explosion.
A Neurobiologist Thinks Big — and Small
By developing new tools for visualizing subcellular structure and activity in molecular detail, Ed Boyden advances on his goal of understanding how the brain works.
Bacteria Sacrifice DNA Repair for Better RNA
Preserving its DNA ought to be a cell’s top priority. But bacteria slow their DNA repair to a crawl in favor of proofreading gene transcripts.
Genetic Struggles Within Cells May Create New Species
Mitonuclear conflict — a struggle between the genes in a cell’s nucleus and its mitochondria — might sometimes split species in two.
Cell Atlases Reveal Biology’s Frontiers
New techniques expose unexpected diversity within seemingly uniform tissues.