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Developmental biology

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To Heal Some Wounds, Adult Cells Turn More Fetal

August 29, 2018

Once again, body cells reveal unexpected plasticity: In a newly discovered type of wound healing, which some researchers call “paligenosis,” adult cells revert to a more fetal state.

Salamander’s Genome Guards Secrets of Limb Regrowth

July 2, 2018

With a fully sequenced genome in hand, scientists hope they are finally poised to learn how axolotls regenerate lost body parts.

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The Physics of Glass Opens a Window Into Biology

June 11, 2018

The physicist Lisa Manning studies the dynamics of glassy materials to understand embryonic development and disease.

Cell by Cell, Scientists Map the Genetic Steps as Eggs Become Animals

April 26, 2018

For the first time, researchers have traced the genetic programs that guide the development of each cell in early embryos. Surprisingly, even cells that start out different can end up the same.

Brainless Embryos Suggest Bioelectricity Guides Growth

March 13, 2018

Researchers are building a case that long before the nervous system works, the brain sends crucial bioelectric signals to guide the growth of embryonic tissues.

Tissue Engineers Hack Life’s Code for 3-D Folded Shapes

January 25, 2018

Mechanical tension between tethered cells cues developing tissues to fold. Researchers can now program synthetic tissue to make coils, cubes and rippling plates.

The Oldest Mini-Brains Have Lifelike Young Cells

August 29, 2017

"Organoid" brain tissue models grown in a lab for two years can help scientists study a critical period of development just before and after birth.

Mini-Brains Go Modular

August 9, 2017

To create a good living replica of the human brain, your best hope may be to let “organoid” components assemble it for you.

How Life Turns Asymmetric

January 31, 2017

Scientists are uncovering how our bodies — and everything within them — tell right from left.

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