Genomics

Depression has often been blamed on low levels of serotonin in the brain. That answer is insufficient, but alternatives are coming into view and changing our understanding of the disease.

The discovery of a hot spot for horizontal gene transfer draws attention to the possible roles of parasites and ecology in such changes.

Svante Pääbo has been awarded the 2022 Nobel Prize in Physiology or Medicine for studying our extinct ancestors’ DNA.

Several projects are aiming to bring back mammoths and other species that have vanished from the planet. Whether that’s technically possible is beside the point.

Large blocks of genes conserved through hundreds of millions of years of evolution hint at how the first animal chromosomes came to be.

The detailed understanding of brains and multicellular bodies reached new heights this year, while the genomes of the COVID-19 virus and various organisms yielded more surprises.

A painstaking study of wing morphology shows both the striking uniformity of individuals in a species and a subtle pattern of linked variations that evolution can exploit.

Driven by her fascination with highly repetitive, hard-to-read parts of our DNA, Karen Miga led a coalition of researchers to finish sequencing the human genome after almost two decades.

Scientists have reported large DNA structures in some archaea that defy easy categorization.